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Assessment of myocardial ischemia in patients with intermediate coronary stenosis based on atomic magnetometer magnetocardiography(MCG): a prospective cohort study

Assessment of myocardial ischemia in patients with intermediate coronary stenosis based on atomic magnetometer magnetocardiography(MCG): a prospective cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300072382
Enrollment
Unknown
Registered
2023-06-12
Start date
2023-06-30
Completion date
Unknown
Last updated
2023-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary artery disease

Interventions

Sponsors

Beijing Anzhen Hosptial, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Age 18-80 years old; (2) With typical symptoms of angina pectoris (CCS grade II or above); (3) CCTA indicates 40-90% stenosis of the main coronary artery (because CCTA may overestimate the degree of stenosis compared with coronary angiography); (4) Intending to be admitted to the hospital for coronary angiography; (5) Participate in this study with informed consent and provide personal information.

Exclusion criteria

Exclusion criteria: (1) Acute myocardial infarction; (2) Old myocardial infarction; (3) Complex arrhythmias, such as frequent atrial premature beats, premature ventricular beats, atrial fibrillation, atrial flutter, etc.; (4) After PCI/CABG; (5) History of congenital heart disease; (6) Definitely diagnosed cardiomyopathy; (7) Abnormal origin or development of coronary arteries; (8) CCTA indicates multi-vessel disease (=2 main coronary artery stenosis >50%); (9) CCTA shows left main lesion (LM stenosis > 50%); (10) Severe coronary artery calcification (CCTA calcification score > 400); (11) Patients with pacemaker surgery and drug pump implantation; (12) There are metal implants such as steel plates and nails in the trunk; (13) Patients who suffer from claustrophobia and cannot lie still for 2 minutes in a closed environment; (14) Subjects considered by the investigators to be unsuitable for inclusion for other reasons; (15) The most severe stenosis of coronary artery <40%; (16) The worst stenosis of coronary artery = 90% (received interventional therapy); (17) For patients with coronary artery stenosis between 70-89%, the operator decides to directly intervene or perform FFR evaluation; (18) The subjects refused to accept the FFR examination.

Design outcomes

Primary

MeasureTime frame
Area under the Curve(AUC);Field map angle at peak;current angle at peak;Change of the map angle within RT interval;Multi-polarization during the TT interval;abnormal distribution during TT interval; sensitivity;specificity;positive predictive value;negative predictive value;The change of the distance between the two poles of the TT magnetic field;T peak magnetic field amplitude;

Countries

China

Contacts

Public ContactXiantao Song

Department of Cardiology, Anzhen Hospital, Capital Medical University

song0929@mail.ccmu.edu.cn+86 133 7010 3538

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 5, 2026