coronary artery disease
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Age 18-80 years old; (2) With typical symptoms of angina pectoris (CCS grade II or above); (3) CCTA indicates 40-90% stenosis of the main coronary artery (because CCTA may overestimate the degree of stenosis compared with coronary angiography); (4) Intending to be admitted to the hospital for coronary angiography; (5) Participate in this study with informed consent and provide personal information.
Exclusion criteria
Exclusion criteria: (1) Acute myocardial infarction; (2) Old myocardial infarction; (3) Complex arrhythmias, such as frequent atrial premature beats, premature ventricular beats, atrial fibrillation, atrial flutter, etc.; (4) After PCI/CABG; (5) History of congenital heart disease; (6) Definitely diagnosed cardiomyopathy; (7) Abnormal origin or development of coronary arteries; (8) CCTA indicates multi-vessel disease (=2 main coronary artery stenosis >50%); (9) CCTA shows left main lesion (LM stenosis > 50%); (10) Severe coronary artery calcification (CCTA calcification score > 400); (11) Patients with pacemaker surgery and drug pump implantation; (12) There are metal implants such as steel plates and nails in the trunk; (13) Patients who suffer from claustrophobia and cannot lie still for 2 minutes in a closed environment; (14) Subjects considered by the investigators to be unsuitable for inclusion for other reasons; (15) The most severe stenosis of coronary artery <40%; (16) The worst stenosis of coronary artery = 90% (received interventional therapy); (17) For patients with coronary artery stenosis between 70-89%, the operator decides to directly intervene or perform FFR evaluation; (18) The subjects refused to accept the FFR examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area under the Curve(AUC);Field map angle at peak;current angle at peak;Change of the map angle within RT interval;Multi-polarization during the TT interval;abnormal distribution during TT interval; sensitivity;specificity;positive predictive value;negative predictive value;The change of the distance between the two poles of the TT magnetic field;T peak magnetic field amplitude; | — |
Countries
China
Contacts
Department of Cardiology, Anzhen Hospital, Capital Medical University