gestational diabetes mellitus
Conditions
Interventions
Regular dietary guidance group:It is suggested that diabetes participants in pregnancy should control blood sugar and reduce the risk of diabetes through diet and exercise intervention, and give appro
Precision low GI high protein dietary pattern group:Participants will wear Huawei bracelets and a continuous blood glucose monitor (CGM) for 2 weeks to collect their heart rate, step count, exercise s
Four different types of standard meals (glucose, noodles, combination rice 1, combination rice 2) were tested for the first meal of 4-7 days of wearing CGM, each containing 50g of available carbohydra
Sponsors
The First Medical Centre of the PLA General Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: ? Diagnosed as GDM ? 20-45 years old ? Pregnancy period is 24-28 weeks ? Single pregnancy ? Chinese nationality, possessing communication and cognitive abilities, and able to undergo regular prenatal examinations ? Willing to participate in this survey and research, subject and family members have signed informed consent forms
Exclusion criteria
Exclusion criteria: 1. Persons with diabetes before the study; The diagnostic criteria for diabetes were fasting plasma glucose = 126 mg/dl [7.0 mmol/L] or 75 g glucose OGTT determination of plasma glucose = 200 mg/dl [11.1 mmol/L] for 2 hours. 2. Twins or multiple pregnancies; 3. Those who suffer from one of the following diseases before or during pregnancy: hypertension, coronary heart disease, or mental illness. 4. Those who have bad habits such as excessive drinking and smoking; 5. Patients with severe malnutrition, severe anemia, or malignant tumors; 6. Persons with acute and chronic infectious diseases, such as hepatitis, HIV, tuberculosis, etc; 7. Gastrointestinal diseases: Self reported chronic hepatitis or cirrhosis, or elevated serum AST or ALT to the following standards: serum AST = 1.5 times the upper limit of normal value, serum ALT = 1.5 times the upper limit of normal value; Previous history of alcoholic hepatitis or alcoholic pancreatitis; Recently, there have been major abdominal surgeries (such as gastrectomy) that are not suitable for inclusion in the study, such as gastroduodenal ulcers, ulcerative colitis, and colon polyps. 8. Renal calculi and renal insufficiency: when serum creatinine is greater than or equal to 1.3mg/dl (115mmol/L), or there is no urinary system infection or vaginal secretion pollution, the quantitative determination of urinary protein is positive. 9. Pulmonary disease: Chronic obstructive airway disease or asthma that requires daily treatment or oxygen therapy at home. 10. Other certain diseases: hyperthyroidism, hypothyroidism, Parkinson's disease, epilepsy, etc; 11. Current or previous participation in other intervention research projects may affect the research effectiveness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| glycated hemoglobin; | — |
Secondary
| Measure | Time frame |
|---|---|
| the proportion of macronutrients in diet;blood glucose;Total serum cholesterol;Serum triglycerides;Serum low-density lipoprotein cholesterol;Serum high-density lipoprotein cholesterol;Delivery method;Basic information of newborns;The incidence of pregnancy complications;Satisfaction with nutritional treatment interventions; | — |
Countries
China
Contacts
Public ContactLIU-Yinghua
Dept of Nutrition, the First Medical Centre of the PLA General Hospital
Outcome results
None listed