sepsis-associated lung injury
Conditions
Interventions
test group:Sodium bicarbonate Ringer injection will be used in intraoperative fluid rehydration therapy.
control group:Compound sodium chloride injection will be used in intraoperative fluid rehydration therapy.
Sponsors
Shanxi Bethune Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: ? All the included cases met the definition and diagnostic criteria of sepsis in the 2016 International Guidelines for Sepsis and Septic Shock; ? Surgery is required; ? =18 years of age; ? ASA?~ ? grade; ? Sign informed consent.
Exclusion criteria
Exclusion criteria: ? Hypermagnesia; ? Patients with chronic pulmonary disease ; ? A history of myocardial infarction within 3 months prior to surgery a history of severe circulatory disease an autoimmune disease a history of psychiatric or neurological disorders that are not properly expressed patients a history of epilepsy a history of hypothyroidism; ? Other conditions deemed inappropriate by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxygenation index;Incidence of ARDS;Total oxidation state(TOS);Total antioxidant status(TAS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Creatinine levels in the blood;Urea nitrogen levels in the blood;Electrolyte levels in the blood;Levels of CC-16 in the blood; | — |
Countries
China
Contacts
Public ContactJiang Xianhong
Shanxi Bethune Hospital
Outcome results
None listed