Bladder cancer
Conditions
Interventions
Case series:None
Sponsors
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Patients who are pathologically diagnosed as bladder cancer and need further drug treatment; 2. Patients with a pathological and/or radiographic diagnosis of myoinvasive bladder cancer (MIBC) and subsequent need for neoadjuvant chemotherapy, immunotherapy, targeted therapy, etc.; 3. Non-muscular invasive bladder cancer (NMIBC) was diagnosed pathologically and the preoperative tumor size was =3cm, high-grade, T1 tumor patients; 4. Age =18 years old, gender unlimited; 5. The ECOG PS status score is 0-1; 6. Able to comply with research and follow-up procedures; 7. The patient has the ability to understand and voluntarily sign the informed consent;
Exclusion criteria
Exclusion criteria: 1. Previous or co-existing other malignant tumors, whose natural history or treatment may interfere; 2. There is a serious or uncontrolled systemic disease; 3. Female patients planning pregnancy or breastfeeding; 4. Severe infections during the 2 weeks prior to study participation, including but not limited to hospitalization due to complications of infection, bacteremia, or severe pneumonia;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IC50 of drugs acting on organoids;Overall response rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall survival;Progression free survival; | — |
Countries
China
Contacts
Public ContactTianxin Lin
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Outcome results
None listed