Postoperative nausea and vomiting
Conditions
Interventions
opioid sparing group:opioid sparing
general anesthesia group:Full dose of opioids
Sponsors
First Affiliated Hospital of University of Science and Technology of China
Eligibility
Sex/Gender
All
Age
19 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Open thyroid surgery was performed at an selected time, Apfel score =2, patients could communicate normally, and could cooperate with the completion of preoperative evaluation and postoperative follow-up; 2. 19~65 years old; 3.ASA ? or ?
Exclusion criteria
Exclusion criteria: 1.Allergic to local anesthetics; 2.Severe liver and kidney dysfunction; 3.Severe cardiovascular and cerebrovascular diseases: cardiac function > Grade II; 4.The state of pregnancy; 5.Patients receiving opioid treatment, substance abuse or drug use for a long time; 6. Patients who do not provide informed consent; 7 Patients who are allergic to NSADIs or have a history of gastrointestinal ulcer surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative nausea and vomiting; | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate (HR) and blood pressure (BP);Intraoperative consumption of propofol and remifentanil;Visual analogue scale scores at 6h, 12h, 24h and 48h after surgery; | — |
Countries
China
Contacts
Public ContactYanhu Xie
First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital)
Outcome results
None listed