Chronic kidney disease stage 5,maintenance hemodialysis
Conditions
Interventions
probiotics group:Take probiotics,Diet instruction
blank control group:Diet instruction
Healthy control group:without
Sponsors
Shanxi Bethune hospital,Shanxi Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: ? The patient is stable; ? Patients can eat normally and take care of themselves; ? No antibiotics, hormones and immunosuppressant drugs were used within 1 month before enrollment; ? no food and drugs containing prebiotics and probiotics have been used in the past half a year; (5) Patients knew the content of this study, voluntarily participated in it and signed the informed consent.
Exclusion criteria
Exclusion criteria: ? with acute and chronic infection; ? Unable to eat normally, need enteral and parenteral nutrition intervention; ? patients with diabetes mellitus; ? Complicated with immune system diseases, tumors, chronic diseases of digestive tract; ? Patients with previous history of cholecystectomy or colectomy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TMA,TMAO;lymphocyte subpopulation;16S V3-V4; | — |
Countries
CHINA
Contacts
Public ContactYan Lv
Shanxi Bethune hospital,Shanxi Academy of Medical Sciences
Outcome results
None listed