Hysteromyoma
Conditions
Interventions
A:Intravenous infusion of 0.3ug/kg sufentanil+1.5mg/kg lidocaine, and continuous pumping of 0.1ug/kg and 2mg/kg respectively until the end of the operation
B:Intravenous infusion of sufentanil 0.3ug/kg + normal saline, and continuous pumping of 0.1ug/kg + normal saline until the end of the operation
Sponsors
Yichang Central People's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1):18-50; 2)ASA ? ?; 3)=180min; 4)BMI 14~35kg/m2.
Exclusion criteria
Exclusion criteria: 1) patients with a history of opioid allergy; 2) analgesic sedatives, antiemetics and anti-pruritus drugs were used 24 hours before surgery; 3) Patients with body temperature higher than 38°C or accompanied by symptoms of acute upper respiratory tract infection within 24 hours before surgery; 4) Patients with a history of bronchial asthma; 5) Patients diagnosed with moderate to severe sleep apnea syndrome before surgery; 6) Patients with difficult airway or previous history of abnormal anesthesia recovery with preoperative assessment; 7) Renal impairment (BUN and or Cr> upper limit of normal values); 8) Liver function impairment (ALT and or AST > 1.5 times the upper limit of normal); 9) Patients with a history of severe head trauma and intracranial hypertension within 6 months; 10) Patients with psychiatric or neurological diseases, or patients who cannot correctly express their wishes; 11) Patients with a history of long-term sedation and analgesic drugs or monoamine oxidase inhibitors; 12) Estimated blood loss during surgery is greater than 100ml; 13) Those who have participated in clinical trials of other drugs in the past month; 14) Patients who cannot undergo ASA or FLACC scoring for various reasons; 15) Patients with other conditions that the investigator considers unsuitable for inclusion. 16) Abnormal breath holding test. 17) Have not quit smoking within the past half month. 18) Patients with uncontrolled hypertension or those with arrhythmias.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nausea and vomiting within 24 hours of surgery;Postoperative VAS score within 24 hours of surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| extubation time;Sedation score;exhaust time;Additional analgesic dose;24-hour QoR-40 score;Vasoactive drug consumption; | — |
Countries
China
Contacts
Public ContactGong Yuan
Yichang Central People's Hospital
Outcome results
None listed