Application of general anesthesia
Conditions
Interventions
Youth group (18~40 years old):According to the success of sedation induced by general anesthesia, the sequential method was used to increase or decrease the induced dose of ciprofol
Middle-aged group (41~65 years old):According to the success of sedation induced by general anesthesia, the sequential method was used to increase or decrease the induced dose of ciprofol
Elderly group (66 ~ 85 years old):According to the success of sedation induced by general anesthesia, the sequential method was used to increase or decrease the induced dose of ciprofol
Sponsors
Boai Hospital of Zhongshan
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Age range from 18 to 85 years old, gender is not limited; 2) Patients undergoing elective tracheal intubation general anesthesia; 3) BMI 18.5 ~ 24.9kg/m2; 4) ASA ? or ? level; 5) Normal head and neck motion, Mallampati ? or ?.
Exclusion criteria
Exclusion criteria: 1) Patients who refuse to participate or are not suitable to participate in this trial; 2) Emergency surgery; 3) Patients with hypovolemia and shock; 4) History of general anesthesia or use of other sedative drugs within 1 month; 5) Allergic to ciprofol , non-depolarizing muscle relaxants, and opioids; 6) Neuromuscular junction disease myasthenia gravis, schizophrenia, severe depression, etc.; 7) Patients with cardiovascular diseases and serious functional impairment of liver, kidney, lung and other important organs; 8) Severe anemia, coagulation dysfunction, etc.; 9) Difficulty in managing respiratory tract; 10) A history of drug and/or alcohol abuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MOAA/S score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Narctored value;MAP, HR, SPO2;Injection pain score;Adverse reactions of perioperative patients; | — |
Countries
China
Contacts
Public ContactLizhen Deng
Boai Hospital of Zhongshan,Southern
Outcome results
None listed