allergic rhinitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1 Each participant must have a diagnosis of PAR according to the diagnostic criteria(3, 8, 9). 2 Aged 18 to 65. No gender limited. 3 Serum-specific IgE test positive for at least one or more of the following allergens: dust mites, house dust, animal fur dander, cockroaches or moulds. 4 Volunteered to participate in the trial and signed an informed consent form. 5 Ability of finishing the case report forms (CRF) by themselves or with the investigators assistance when necessary.
Exclusion criteria
Exclusion criteria: 1 Acute rhinitis (typhoid), vasomotor rhinitis, autonomic rhinitis, eosinophilic non-allergic rhinitis, or serum IgE negative. 2 Local skin lesions on the head and face such as burns, eczema, ulcers, frostbite breakouts. 3 Pregnancy or menstruation (After menstruation can be treated, the dating should be marked). Lactating women. 4 Participants with dysnoesia or behavioral disorders will be unable to cooperate with the study. 5 Participants who are easily lost to follow-up. 6 Those who are using systemic or local hormones for asthma or other diseases. 7 Participants with a history of asthma and currently treated with hormonal drugs. 8 Participants with allergies or contraindications to study drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| total nasal symptom score (TNSS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Rhinoconjunctivitis Quality of Life Questionnaire-standardized score (RQLQs);rhinomanometry;acoustic rhinometry;adverse events (AE);relief medication scores; | — |
Countries
China
Contacts
The Second Affiliated Hospital of Guangzhou University of Chinese Medicine