non-suicide self-injury
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Adolescents who have engaged in at least 5 acts of self-harm within the past year, and have engaged in self-harm at least once within the month prior to assessment; 2. Aged between 12 and 18, regardless of gender; 3. Diagnosed with or without a comorbid depressive disorder using the KSAD-PL; 4. Not currently taking medication and willing to refrain from any medication treatment for the next three months, or currently taking medication (limited to SSRIs and second-generation antipsychotics) without any changes in dosage or type for four consecutive weeks and with no planned medication adjustments for the next three months; 5. Right-handed; 6. No fear of confinement and no metal implants in the body.
Exclusion criteria
Exclusion criteria: 1. Organic mental disorders, bipolar disorder, mental disorders caused by psychoactive substances, schizophrenia and its spectrum disorders, and mental disorders caused by physical diseases; 2. There are currently serious suicidal ideation and behaviors, (using the Suicide ideation and ideation assessment scale, one of the following questions is scored 3 points or more (out of 4 points, the higher the score, the heavier the degree) "How likely do you think there is to be suicidal ideation in the future", "How likely do you think there is to be a suicide plan in the future", "How likely do you think there is to be a suicide attempt in the future";) Requiring hospitalization for treatment, or family members who believe that current non suicidal self injury behavior is unacceptable and require hospitalization for treatment; 3. Having hearing impairment or difficulty understanding language; Currently receiving any form of psychotherapy (individual psychotherapy or group psychotherapy); 4. Currently undergoing physical therapy (such as transcranial magnetic stimulation);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Self-Injurious Thoughts and Behaviors Interview; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hamilton Depressive Symptom Scale;Children Depressive Inventory;Barret-Impulsive Scale;Emotional Reactivity Scale;EMBU;Beck Depression Inventory;Beck Anxiety Inventory;Emotional Film Task;Emotional Odd Ball Task;Odd Ball Task;fMRI;Event Related Potential;TSST test;Genetic methylation levels.; | — |
Countries
China
Contacts
Shenzhen Kangning Hospital