Postoperative cognitive dysfunction
Conditions
Interventions
Electroacupuncture group:Electroacupuncture
Dexmedetomidine group:Dexmedetomidine
Electroacupuncture combined with dexmedetomidine group:Electroacupuncture combined with dexmedetomidine
Sponsors
Jiaxing First Hospital
Eligibility
Sex/Gender
All
Age
45 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1. patients scheduled for knee or hip arthroplasty at Jiaxing First Hospital; 2. ASA classification = grade III; 3. those who could cooperate with the neuropsychological assessment; 4. those who had signed the informed consent; 5. age = 45 years;
Exclusion criteria
Exclusion criteria: Exclusion criteria: 1. coagulation dysfunction or routine use of anticoagulant drugs; 2. previous cognitive dysfunction, aphasia, psychiatric disorders or diseases that affect patient cooperation; 3. severe cardiovascular or cerebrovascular disease that endangers life; 4. electroacupuncture site infection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mini-mental State Examination; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative sedative and analgesic drug dosage;Hospital Anxiety and Depression Scale;s-100ß protein; | — |
Countries
China
Contacts
Public ContactHuadong Ni
Jiaxing First Hospital
Outcome results
None listed