sepsis acute gastrointestinal injury
Conditions
Interventions
Treatment group:Western medicine basic treatment + inflammatory prescription(Yantiao Fang)
Sponsors
Henan Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. 18-80 years; 2. Sepsis and AGI grade II and III diagnosis; 3. Hot colon evidence; 4. Acute onset within 3 days; 5. All patients signed informed consent for the study.
Exclusion criteria
Exclusion criteria: 1. Allergic constitution or allergic to known ingredients of the drug; 2. Patients with severe diarrhea; 3. Intestinal obstruction caused by other causes; 4. Patients with pregnancy, malignant tumors, active gastrointestinal bleeding. 5. Abdominal infection, surgery caused by gastrointestinal dysfunction; 6. Patients with a clear immunodeficiency disease or other immunosuppressive state.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Day-28 mortality;clinical efficiency; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intra-abdominal pressure ;Intestinal mucosal injury index;Symptom score (abdominal pain, abdominal distension, constipation, vomiting, fever) and days of remission.;Gastric reserve;SOFA and APACHE II scores before and after treatment.; | — |
Countries
China
Contacts
Public ContactChen Qian
Henan Provincial Hospital of Traditional Chinese Medicine
Outcome results
None listed