Non-specific Disease
Conditions
Interventions
Intervention Group:Daily oral selenium tablets (Se: 120 µg/d)
Control Group:Daily oral placebo, specific dosage as in the intervention group
Sponsors
Nanjing University (Suzhou) High-Tech Institute/Jiangsu Provincial Center for Disease Prevention and Control (Public Health Research Institute of Jiangsu Province)
Eligibility
Sex/Gender
All
Age
60 Years to 79 Years
Inclusion criteria
Inclusion criteria: 1. Aged 60-79 years; 2. No smoking; 3. No major diseases such as cancers; 4. No acute exacerbation of chronic diseases; 5. No metabolic diseases such as diabetes; 6. No liver or kidney diseases such as hepatitis or nephritis; 7. No mental diseases; 8. Retired and without a history of occupational exposure to toxic substances; 9. There are no plans to move out of their place of residence within the next year; 10. BMI<28 kg/m2; 11. Have lived at the study site for more than 5 years.
Exclusion criteria
Exclusion criteria: 1. Take selenium containing nutritional supplements regularly on daily life; 2. Allergies to selenium supplements or placebo components in this study; 3. Suffering from hearing, language, and cognitive impairments that prevent normal communication; 4. Have a history of using antibiotics, hormones, anti-inflammatory or other drugs one month before enrollment; 5. Have a history of fever or infection within one month before enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Contents of Se;Blood biochemical parameters;Routine Blood Test;Weakness level;Contents of Cd;Blood Pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammatory Indicators;Oxidative Stress Indicators;Metabolite;Health perception; | — |
Countries
China
Contacts
Public ContactLei Huang, Hong Sun
Nanjing University (Suzhou) High-Tech Institute/Jiangsu Provincial Center for Disease Prevention and Control (Public Health Research Institute of Jiangsu Province)
Outcome results
None listed