Effects of inspired oxygen concentrations during anesthesia awakening on postoperative atelectasis after laparoscopic radical gastrectomy for gastric cancer: a randomized controlled trial

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300072210

Enrollment

Unknown

Registered

2023-06-07

Start date

2023-04-03

Completion date

Unknown

Last updated

2023-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric cancer

Interventions

Low FiO2 group:40% FiO2

High FiO2 group:100% FiO2

Eligibility

Sex/Gender

All

Age

65 Years to 89 Years

Inclusion criteria

Inclusion criteria: 1) Patients undergoing laparoscopic radical gastrectomy that was expected to be more than 3h 2) Patients more than 65 years old and with American Society of Anaesthesiologists physical status I–III 3) Body mass index18.5~25 kg/m2 4) No obvious abnormalities in lung function, no invertebrate or thoracic malformations, no difficult airway, asthma, or COPD 5) After fully explaining the content of the clinical trial, volunteers to join and sign informed consent

Exclusion criteria

Exclusion criteria: 1) Illness with symptoms of upper respiratory tract infection or lung infection in the last 4 weeks, and chest X-rays suggest pneumonia;Severe lung diseases such as chronic obstructive pulmonary disease, pleural effusion, asthma, pneumothorax, diseases affecting lung and thoracic compliance, and a history of lung surgery such as lobectomy 2) Complicated with serious diseases, including severe liver and kidney injury, autoimmune diseases, immune deficiency, cardiovascular and cerebrovascular diseases, neuropsychiatric diseases, blood diseases, etc 3) Preoperative oxygen saturation was less than 90% 4) Poor compliance, difficult to cooperate with treatment and follow-up 5) Participated in other clinical studies in the past 3 months; 6) The researchers believe that the subjects are not suitable to participate in the study due to other reasons.

Design outcomes

Primary

Measure	Time frame
Postoperative pulmonary ultrasound score results;	—

Secondary

Measure	Time frame
Lung function 1 day before surgery and 1, 3 and 5 days after surgery;Arterial blood gas analysis;Pulmonary complications 1, 3, and 5 days after surgery;	—

Countries

China

Contacts

Public ContactLiYun

The Second Affiliated Hospital of Anhui Medical University

yunli_001@aliyun.com+86 151 0551 7565

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026