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Clinical Research of Individual Mandibular and Temporomandibular Joint Defect Reconstruction

Clinical Research of Individual Mandibular and Temporomandibular Joint Defect Reconstruction

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300072209
Enrollment
Unknown
Registered
2023-06-07
Start date
2019-04-09
Completion date
Unknown
Last updated
2023-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mandibular and Temporomandibular Joint Defect

Interventions

Individual mandibular and TMJ prosthesis reconstruction group:Individual mandibular and temporomandibular joint prostheses were used to reconstruct the bone defect
Conventional reconstructed plate reconstruction group:Conventional reconstructed plate was used to reconstruct the bone defect

Sponsors

the Chinese PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients with large area obvious bone destruction of mandible after radiological examination, who were diagnosed with mandibular cyst, ameloblastoma or other malignancies requiring mandibular segmental osteotomy. Temporomandibular joint reconstruction in patients with benign and malignant tumors displayed severe bone destruction after radiological examination, or TMJ ankylosis.

Exclusion criteria

Exclusion criteria: Exclusion criteria: poorly controlled diabetic patients, patients with serious cardiovascular and other cerebrovascular diseases or other systemic diseases who could not tolerate general anesthesia surgery, patients taking bisphosphonate and other inhibitors of bone metabolism, patients undergoing radiotherapy or chemotherapy recently, and pregnant patients.

Design outcomes

Primary

MeasureTime frame
Prothesis fracture;Prothesis exposure;

Secondary

MeasureTime frame
Prothesis loosen;Infection;

Countries

China

Contacts

Public ContactMin Hu

the Chinese PLA General Hospital

humin48@vip.163.com+86 139 1033 8265

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 10, 2026