fibrobronchoscopy
Conditions
Interventions
X-1 group (air excision - routine group):lidocaine was injected through the air incision
X-2 group (air excision - optimization group 1):airtight atomization of lidocaine through the air incision was carried out. When entering the lens to the carinal process, lidocaine was sprayed into t
X-3 group (air excision - optimization group 2): lidocaine was injected through the air incision, and lidocaine was sprayed into the left and right bronchi via the bronchus, respectively, at the poin
Y-1 group (intubation - routine group): lidocaine was injected through the tracheal intubation port
Y-2 group (intubation - optimization group) : lidocaine was injected into the lateral wall of endotracheal intubation, and lidocaine was injected into the endotracheal intubation orifice, and lidocai
EX group (esketamine-mechanical ventilation group):Esketamine
FX group (fentanyl-mechanical ventilation group):Fentanyl citrate
EN group (esketamine-non-mechanical ventilation group):Esketamine
FN group (fentanyl-non-mechanical ventilation group):Fentanyl citrate
Sponsors
Tianjin Medical University General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Intensive care unit adult patients aged 18 to 80 years who undergoing fibrobronchoscopy; Patients voluntarily participated in the study and signed informed consent.
Exclusion criteria
Exclusion criteria: Patients with severe organ dysfunction,such as shock state, rescue state; Patients with a history of mental illness and abuse of sedatives; Patients who are allergic to the drug under study and have contraindications; People with severe communication disabilities; Other conditions that do not respond to airway stimulation; Patients or their family members declined to participate in the studysuch as shock state, rescue state
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of sedation and analgesia ;incidence of hypotension;incidence of hypoxemia;cough and body movement; | — |
Secondary
| Measure | Time frame |
|---|---|
| patient and operator satisfaction;incidence of other adverse reactions such as bronchospasm, cough, increased secretion, bradycardia, tachycardia, vomiting, bleeding, and agitation; | — |
Countries
China
Contacts
Public ContactKeLiang Xie
Tianjin Medical University General Hospital
Outcome results
None listed