Femoral Neck Fracture
Conditions
Interventions
Test arm:cannulated compression screws+2mg of rhBMP-2
Control arm:cannulated compression screws
Sponsors
The Third Hospital of Hebei Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Willing to join the study and sign the informed consent form; 2. Male or female patients aged 18-40 years; 3. Those who have a clear history of trauma, are definitely diagnosed as a new Garden III or above neck of femur fracture by imaging examination, and plan to receive hollow screw internal fixation; 4. Admission to hospital after injury <= 72 h.
Exclusion criteria
Exclusion criteria: 1. Previous hip surgery, ipsilateral hip or femoral dysplasia; 2. Multiple injuries (such as injury severity scale ISS > 16) or accompanied by ipsilateral lower limb fractures, femoral head fractures, pelvic or acetabular fractures; 3. Pathological or old fractures (injury to surgery >= 2 weeks); 4. Patients with other diseases affecting surgery and rehabilitation, such as metabolic bone disease, poliomyelitis sequelae, sequelae of poliomyelitis, a history of poor bone union,and diabetes; 5.A history of endocrine or metabolic disorders known to affect osteogenesis (e.g., renal osteodystrophy, hyperthyroidism, parathyroid disorders, Ehler-Danlos syndrome, osteogenesis imperfecta, calcium imbalance) 6. Patients with severe cardiac and renal insufficiency, liver damage, hematopoietic dysfunction, and severe tumor history; 7. Patients who received open reduction during surgery; 8. Patients with obvious surgical contraindications; 9. Patients who require systemic glucocorticoid therapy; 10. Pregnant or lactating women, as well as those who plan to conceive during the trial period.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| rate of fracture union;Harris hip score;Surgical complications; | — |
Primary
| Measure | Time frame |
|---|---|
| time of fracture union ; | — |
Countries
China
Contacts
Public ContactZhiyong Hou
The Third Hospital of Hebei Medical University
Outcome results
None listed