Congenital syphilis
Conditions
Interventions
Group of congenital syphilis:None
Sponsors
Children's Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
No minimum to 3 Years
Inclusion criteria
Inclusion criteria: Congenital syphilis confirmed during hospitalization: Children born to pregnant women with syphilis infection can be diagnosed as congenital syphilis if they meet any of the following criteria: 1). The child's skin and mucous membrane damage or tissue samples have positive pathogenic tests (pathogenic testing methods include dark field microscopy, silver staining microscopy, and nucleic acid amplification test); 2) Positive IgM antibody test for Treponema pallidum at birth; 3) The quantitative test result of non syphilitic spirochete serological test at birth is positive, with a titer greater than or equal to 4 times the mother's pre delivery titer (2 dilutions), and the syphilitic spirochete serological test result is positive; 4) Children who cannot be diagnosed with congenital syphilis at birth, and whose non Treponema pallidum serological test results change from negative to positive or increase by 4 times the titer (2 dilutions) during any follow-up process, and whose Treponema pallidum serological test is positive; 5) Children who have not been diagnosed with congenital syphilis before 18 months of age still have positive serological tests for Treponema pallidum after 18 months of age.
Exclusion criteria
Exclusion criteria: Does not meet diagnostic criteria
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Congenital syphilis incidence rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of syphilitic encephalitis; | — |
Countries
China
Contacts
Public ContactShi yuan
No. 136, Zhongshan 2nd Road, Yuzhong District, Chongqing
Outcome results
None listed