depression
Conditions
Interventions
sMRI-guided rTMS group:sMRI-guided rTMS(Choose the left DLPFC as the target, precise positioning by neuronavigation, guided by the magnetic resonance image of the patient's structure, and the precise
Traditional rTMS group:Traditional rTMS(Choose the left DLPFC as the target, and use the method of "moving the motor cortex forward 5cm". The rTMS coil stimulates the motor cortex to determine the pos
Health Control:None
Sponsors
Shenzhen Kangning Hospital
Eligibility
Sex/Gender
All
Age
12 Years to 18 Years
Inclusion criteria
Inclusion criteria: Depression group enrollment criteria: ? age range: 12-17 years old; ? DSM-5 diagnostic criteria for diagnosis of depressive disorder; ?right-handed. Admission criteria for healthy subjects:? Age 12-18 years old; ?No previous or current mental illness, no serious or unstable heart, liver, kidney, endocrine, blood and other medical and nervous system diseases; ?Right-handed.
Exclusion criteria
Exclusion criteria: Exclusion criteria for depression group: ?Patients with severe or unstable heart, liver, kidney, endocrine, blood and other medical diseases; ?Patients with other DSM-5 mental disorders; ?Patients with a history of neurological diseases or craniocerebral trauma; ?MRI examination Contraindications; ?Other conditions considered by the investigators to be unsuitable for participating in clinical trials. Exclusion criteria for health group: ? a history of suicide attempt, severe non-suicidal self-injuriou behavior, suicidal behavior in the waiting period; ? Contraindications for MRI examination; ? Other conditions that the investigator believes are not suitable for participating in clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton's Depression Scale -17; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hamilton Depressive Symptom Scale; | — |
Countries
China
Contacts
Public ContactNana Liang/Jianping Lu
Shenzhen Kangning Hospital
Outcome results
None listed