Gastric cancer
Conditions
Interventions
Control group:Normal saline was used for control during perioperative period
Esketamine group:Esketamine was used perioperatively
Sponsors
The First Affiliated Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 95 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: (1) American Society of Anesthesiologists (ASA) medical condition I~II, no respiratory or circulatory disorders, no chronic pain, definite diagnosis of gastric cancer (refer to the diagnostic criteria of Health Industry of the People's Republic of China: Diagnostic Criteria for Gastric Cancer (WS 316-2010)). (2) Patients who were willing to receive PCIA after elective laparoscopic surgery for gastric cancer. (3) The age range is over 18 years old. (4) Able to understand the procedures and methods of this study and willing to sign the informed consent.
Exclusion criteria
Exclusion criteria: Exclusion criteria: (1) History of radiotherapy and chemotherapy for gastric cancer. (2) Have mental disorders, mental disorders and other diseases. (3) A history of depression. (4) Severe hypertension, coronary heart disease, cardiac insufficiency, pulmonary hypertension, cranial or ocular hypertension, hyperthyroidism, etc. (5) Patients with allergic history of the drugs used in this study. (6) Emergency surgery or trauma patients. (7) It is expected that the operation time will be long, there is the possibility of large amount of blood loss, or there is laparotomy transfer during the operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative depression;Postoperative anxiety;Postoperative fatigue;PT;APTT; | — |
Countries
China
Contacts
Public ContactGeng Wujun
The First Affiliated Hospital of Wenzhou Medical University
Outcome results
None listed