elective caserean section
Conditions
Interventions
opioid-free group:Intravenous infusion of esketamine 0.15mg / kg and lidocaine 1.5mg / kg
control group:Intravenous infusion of sufentanyl at 0.3mg / kg, and the same appearance of normal saline
Sponsors
Yichang Central People’s Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1) Age: 18-35 years old; 2) ASA grade; 3) For elective cesarean section; 4) Agree to participate in the questionnaire survey.
Exclusion criteria
Exclusion criteria: 1) Pregnant women with other diseases and not well controlled, such as hypertension, diabetes, chronic pain, epilepsy, asthma, renal function impairment (BUN and or Cr> 2 times normal value), liver function impairment (ALT and OT AST> 1.5 times normal value), etc.; 2) Combined with special obstetric conditions: placental abruption, placenta previa with bleeding, fetal abnormalities, twin or multiple pregnancy; 3) Pregnant women who need an emergency caesarean section due to special circumstances, such as fever with acute infection, trauma, premature rupture of membranes with fetal distress, etc.; 4) Pregnant women with allergies to any anesthetic ingredients; 5) Reuse, disagree, failure to understand the scale survey or anesthesia protocol; 6) Patients with other circumstances considered not suitable for inclusion;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| time weighted average of postoperative pain scores;apgar scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood and gas analysis of umbilical artery and vein;Intraoperative hemodynamic parameters; | — |
Countries
China
Contacts
Public ContactYuan Gong
School of Basic Medicine of Three Gorges University, First Clinical Medical College of Three Gorges University, Yichang Central People's Hospital
Outcome results
None listed