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The effect of subanaesthetic dose of esketamine during induction on anesthesia recovery in PACU:a retrospective cohort study

The effect of subanaesthetic dose of esketamine during induction on anesthesia recovery in PACU

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300072154
Enrollment
Unknown
Registered
2023-06-05
Start date
2023-06-01
Completion date
Unknown
Last updated
2023-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abdominal diseases

Interventions

Induction with esketamine group:N/A

Sponsors

The First Affiliated Hospital, Zhejiang University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1 Patients who have underwent abdominal surgery (including hepatobiliary and pancreatic surgery, gastrointestinal surgery, and colorectal surgery) at the headquarters of the First Affiliated Hospital of Zhejiang University School of Medicine during 2022.12.20-2023.5.18; 2. General anesthesia induction with esketamine or routine induction during the same period; 3. Age> 18 years old; 4. ASA grade ?-III; 5. general anesthesia for endotracheal intubation.

Exclusion criteria

Exclusion criteria: 1. Patients with hepatic and renal insufficiency; 2. patients with severe pulmonary disease; 3. patients with congestive heart failure and reduced cardiac output; 4. patients with disordered central nervous system; 5. patients with mental illness; 6. patients with intraoperative severe bleeding; 7. patients with unscheduled postoperative ICU delivery; 8. patients with contraindications of esketamine use, such as hypertension 180 / 100mmHg, hyperthyroidism, atrial fibrillation, etc.

Design outcomes

Primary

MeasureTime frame
Anesthesia recovery time;

Secondary

MeasureTime frame
Stay length in PACU;Postoperative pain score;The occurrence of hypertension and hypotension;The occurrence of delirium and agitation occur;The occurrence of respiratory depression;The occurrence of nausea and vomiting;

Countries

China

Contacts

Public ContactDongdong Wang

The First Affiliated Hospital, Zhejiang University School of Medicine

gregwd@163.com+86 137 7780 2903

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026