Abdominal diseases
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1 Patients who have underwent abdominal surgery (including hepatobiliary and pancreatic surgery, gastrointestinal surgery, and colorectal surgery) at the headquarters of the First Affiliated Hospital of Zhejiang University School of Medicine during 2022.12.20-2023.5.18; 2. General anesthesia induction with esketamine or routine induction during the same period; 3. Age> 18 years old; 4. ASA grade ?-III; 5. general anesthesia for endotracheal intubation.
Exclusion criteria
Exclusion criteria: 1. Patients with hepatic and renal insufficiency; 2. patients with severe pulmonary disease; 3. patients with congestive heart failure and reduced cardiac output; 4. patients with disordered central nervous system; 5. patients with mental illness; 6. patients with intraoperative severe bleeding; 7. patients with unscheduled postoperative ICU delivery; 8. patients with contraindications of esketamine use, such as hypertension 180 / 100mmHg, hyperthyroidism, atrial fibrillation, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anesthesia recovery time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Stay length in PACU;Postoperative pain score;The occurrence of hypertension and hypotension;The occurrence of delirium and agitation occur;The occurrence of respiratory depression;The occurrence of nausea and vomiting; | — |
Countries
China
Contacts
The First Affiliated Hospital, Zhejiang University School of Medicine