Acute radiation pneumonitis
Conditions
Interventions
Control group:No
Experimental group:Oral Shabairunfei formula for 60 days
Sponsors
Shanxi Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Patients over 18 years of age who will receive radiotherapy for tumors with an irradiation field that includes the lungs, regardless of gender (2) KPS score = 60 (3) Expected survival = 3 months (4) Expected to receive = 60 days of trial drug treatment (5) Radiotherapy plan with a total dose of 8Gy or more to the lungs (6) No infection before radiotherapy (7) The patient agrees to participate in this trial and has signed an informed consent form
Exclusion criteria
Exclusion criteria: (1) Those who fast or oppose taking the test drug (2) Combination of serious non-neoplastic cardiac or pulmonary primary diseases, such as acute exacerbation of chronic bronchitis, pulmonary heart disease, pulmonary embolism, FEV1/FVC <70%, and FEV1 <50% (predicted), or other serious diseases, such as bronchial fistula (3) Brain metastases or other diseases that cause mental impairment of consciousness and inability to cooperate (4) Pregnant or lactating women (5) Allergy and allergy to the test drug or control placebo (6) Previously treated with chest radiotherapy (7) White blood cell <4.0×10^9/L or hemoglobin <80g/L before treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incident of acute radiation pneumonitis;Acute radiation lung injury RTOG classification; | — |
Secondary
| Measure | Time frame |
|---|---|
| TCM susceptibility points;KPS score;Serum specific index of IL-6 IL-8 TNF-a; | — |
Countries
China
Contacts
Public ContactDing Hao
Shanxi Chinese Medicine Hospital
Outcome results
None listed