Hypertension
Conditions
Interventions
200mg once a day in the morning:sakubactrovalsartan 200mg once a day in the morning
200mg once a day at night:sakubactrovalsartan 200mg once a day at night
100mg twice a day:sakubactrovalsartan 100mg twice a day
Sponsors
Shaanxi Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 18 and 75 2. Patients with hypertension (Grade 1-2)
Exclusion criteria
Exclusion criteria: 1.Hypertension Grade 3 (SBP=180mmHg and/or DBP=110mmHg) 2.Secondary hypertension 3.Congestive heart failure 4.Blood potassium>5.2 mmol/L 5.eGFR<30 mL/min/1.73m2 6.History of angioedema 7.Malignant tumor 8.Pregnant and lactating women 9.Participate in other medical experiments at the same time
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes of blood pressure in the morning after 24 weeks;Changes of nocturnal blood pressure after 24 weeks; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes of 24-h mean blood pressure after 24 weeks;Changes of daily blood pressure after 24 weeks;Changes of structure and function of left atrium;Changes of structure and function of left ventricle;Changes of neuropeptide substance; | — |
Countries
China
Contacts
Public ContactLiang Lei
Shaanxi Provincial People's Hospital
Outcome results
None listed