coronary heart disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? Patients who require continuous coronary artery bypass grafting surgery with small incisions (including single or multiple branches); ? Age 18-80 years old; ? The American Society of Anesthesiologists (ASA) grading is III to IV; ? Sign an informed consent form;
Exclusion criteria
Exclusion criteria: ? Contraindications to the placement of occluder: such as anatomical abnormalities of trachea and bronchus, tracheobronchial tumors, and operations involving the main bronchus (pneumonectomy); ? Patients with morbid obesity [body mass index (BMI)>35 kg/m2]; ? Severe systemic diseases such as sepsis and other systemic infections, severe COPD (pre operative lung function examination showing forced expiratory volume in the first second (FEV1)<50% of the expected value), respiratory diseases such as asthma, and severe liver and kidney dysfunction; ? Suspected or known difficult airway: including a history of head and neck malignant tumors or radiation therapy, known history of difficult intubation, modified Mallampati grade III-IV, mouth opening<3.5 cm or nail chin spacing<6.5 cm, etc; ? Unable to cooperate with the researcher for any reason;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tracheal intubation time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of intubations and first success rate;Intraoperative lung collapse score;Total number of corrections and total correction time;Airway plateau pressure and peak pressure during 10 and 30 minutes of single lung ventilation;Incidence of hypoxemia;Postoperative complications;QoR-15 scores at 24 and 48 hours after extubation;Collection of blood samples and detection of biochemical indicators;Hemodynamic indicators; | — |
Countries
China
Contacts
Peking University Third Hospital