Septic cardiomyopathy
Conditions
Interventions
SIMD:N
S:None
Sponsors
Changshu No.1 People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: (1) Western medicine diagnosis: In accordance with the sepsis diagnosis listed in the "Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021", the patient has an infection and the degree of change in the Sequential Organ Failure Assessment (SOFA) is = 2 points. (2) Age = 18 years old, (3) All included patients or family members voluntarily participate in the trial and sign the "Clinical Research Informed Consent Form".
Exclusion criteria
Exclusion criteria: (1) Patients with clear heart valve disease, acute coronary syndrome, and severe heart failure; (2) Patients undergoing cardiothoracic surgery, patients after cardiopulmonary resuscitation, chest trauma; (3) Completeness left bundle branch block; (4) Severe pulmonary insufficiency such as pulmonary embolism; (5) Patients with advanced malignant tumors, hematological diseases, chronic liver and kidney dysfunction, and immune diseases; (6) Existence of severe central nervous system lesions; (7) Merge patients with various acute and chronic infectious diseases; (8) Patients participating in clinical trials of other drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NLRP3;cTnI; | — |
Secondary
| Measure | Time frame |
|---|---|
| TNF-a;IL-1;IL-6;IL-1ß;IL-10; | — |
Countries
China
Contacts
Public ContactZhou Weiyi
Changshu No.1 People's Hospital
Outcome results
None listed