colorectal cancer
Conditions
Interventions
Group Control:Intravenous propofol
Group1:Remidazolam 0.3mg/kg i.v
Group2:Remazolam 6mg/kg/h by intravenous pump
Group3:Remidazolam 12mg/kg/h by intravenous pump
Sponsors
The Fourth Hospital of Hebei Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: American Society of Anesthesia (ASA) physical status classification ?-?;Age 18-80 years;Body mass index ( BMI ) was 18.5-28 kg / m2. No sedative or analgesic allergy history ; no history of allergic disease or mental illness ; not long-term use of sedative and analgesic drugs ; no opioid dependence or tolerance ; no bradycardia ; no brain loss or intracranial hypertension ; there was no obvious abnormality in heart, lung, liver and kidney function. They agreed to participate in this study and signed informed consent.
Exclusion criteria
Exclusion criteria: Patients or their families refused to participate in the trial, elderly patients ( age > 80 years old ), patients allergic to benzodiazepines and any components of the product, patients with myasthenia gravis, schizophrenia, and patients with severe depression.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| systolic arterial pressure;arterial diastolic pressure;Mean arterial pressure;Heart rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| onset;Total dose of induction medication; | — |
Countries
China
Contacts
Public ContactHuaqin Liu
The Fourth Hospital of Hebei Medical University
Outcome results
None listed