hemodialysis
Conditions
Interventions
Intradialytic cycling group:Moderate-intensity aerobic intradialytic cycling exercise on dialysis is performed 3 times a week for 12 weeks, and each exercise is carried out at 0~2h of dialysis. The ex
In the active exercise stage, the patient performs active treadmill exercise, the speed is maintained at 40-50, the time is 30 minutes, the treadmill resistance starts from level 0, and increases by a
The relaxation phase lasts 5 minutes, which is the same as the warm-up phase.
Respiratory training group:On the basis of routine hemodialysis care, 12 weeks of intra-dialysis breathing training is performed three times a week, with a total of three training methods. (1) Lip pur
(2) Abdominal breathing training: the patient's hip and knee joints are slightly flexed, and the patient is instructed to place the non-ostomy hand on the abdomen, slowly inhale deeply through the nos
(3) Resistance breathing training: small sandbags of different
Sponsors
The First Affiliated Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria for uremia stage of chronic renal failure in the 4th edition of Nephrology; (2) hemodialysis by autologous arteriovenous fistula; (3) Hemodialysis time between 3 months - 20 years, 4h/time, 3 times/week, stable clinical condition (not hospitalized in the past 30 days); (4) Age: 18-70 years old (inclusive); (5) BMI: 18-32.5 (normal - mild obesity); (6) Cardiac function: left ventricular ejection fraction= 50%; NYHA = Class I; Weber heart function grade A and B; (7) The level of physical activity of individuals in the International Physical Activity Questionnaire (IPAQ) reached a medium or high level; (8) The condition is stable and clear; (9) Voluntarily participate in this study and sign an informed consent form
Exclusion criteria
Exclusion criteria: (1) The initial stage of dialysis program and medication program change; (2) weight gain between dialysis >5% dry body weight; (3) Patients with bloodborne infectious diseases such as viral hepatitis B, viral hepatitis C, syphilis and AIDS; (4) Abnormal blood pressure: severe hypertension (such as blood pressure more than 180/110mmHg), or hypotension (<90/60mmHg); Cardiopulmonary diseases: severe heart failure, arrhythmia, unstable angina, severe pericardial effusion, valve stenosis, hypertrophic cardiomyopathy, aortic dissection, etc., uncontrolled pulmonary hypertension; (5) Acute clinical events: acute systemic inflammatory diseases or the use of antibiotics in the past 30 days; (6) retinopathy; (7) Diabetes mellitus that does not control blood sugar well; (8) Severe anemia (Hb<60g/L); (9) Symptoms of deep vein thrombosis, such as abnormal edema, redness and pain in the calves; (10) Renal osteodystrophy or exercise that has occurred fractures may aggravate joint and bone lesions; (11) Cognitive impairment, communication disorders and mental illness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PeakVO2;AT;vital capacity;Forced vital capacity;Maximum ventilation;Quality of life; | — |
Secondary
| Measure | Time frame |
|---|---|
| 30 seconds sitting and standing time;Ability to perform activities of daily living; | — |
Countries
China
Contacts
Public ContactGuangxu Xu
The First Affiliated Hospital of Nanjing Medical University
Outcome results
None listed