novel coronavirus infection
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Age: 18-80 years old. (2) The patient has had a positive result of nucleic acid test or antigen self-test of novel coronavirus or a history of COVID-19 related epidemiology. (3) Cough lasted for more than 3 weeks. (4) Patients must sign informed consent before being enrolled in the cohort, and can participate in the study protocol and follow up according to the protocol.
Exclusion criteria
Exclusion criteria: (1) A history of asthma with a definite diagnosis. (2) Used systemic corticosteroids, ICS or ICS combined with LABA, or ICS combined with LABA+LAMA during the four weeks prior to enrollment; Or acute respiratory tract infection; Or lung CT with significant lung inflammation. (3) Serious systemic diseases or chronic respiratory diseases with clear diagnosis in the past, such as heart failure, kidney failure, liver failure (the underlying disease is stable, and the original medication regimen should be maintained as long as the drug is maintained), COPD, cystic fibrosis, bronchiectasis, interstitial lung disease, tuberculosis, lung cancer, etc. (4) Patients who have known significant risk factors for cough, including, but not limited to, the use of ACEI/ARB drugs. (5) Women of childbearing age who are currently pregnant or lactating. (6) Received immunosuppressive therapy or participated in clinical investigators 3 months before enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cough evaluation test, CET;Leicester Cough Questionnaire, LCQ;VAS; | — |
Secondary
| Measure | Time frame |
|---|---|
| lung function;airway inflammation; | — |
Countries
China
Contacts
Shandong Provincial Hospital