Attention-deficit/Hyperactivity Disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria for adults with ADHD: 1 ) =18 years old; 2 ) with a diagnosis of adult ADHD through Conners Adult ADHD Diagnostic Interview based on DSM-5, and a Clinical Global Impression Scale (CGI-S)=3 confirmed by the attending physician and above psychiatrists; 3) Without use of medication, or stable use of medication (drug fuctuations<10% for at least 1 month), either methylphenidate hydrochloride controlled-release tablets (Concerta) or atomoxetine hydrochloride (Strattera). Inclusion criteria for healthy controls: Healthy adults with age and sex-matched with the ADHD patients.
Exclusion criteria
Exclusion criteria: Exclusion criteria for adults with ADHD: 1) Patients with current severe mental disorders, including psychotic disorders, current mania episode of bipolar disorder, severe depressive episodes with psychotic symptoms or high risk of suicide/self-injury, severe panic disorder, substance dependence, autism spectrum disorder, substance abuse, and antisocial personality disorder; 2) Those with intelligence below the normal range; 3) Those with high suicide risk; 4) Those with unstable physical conditions (such as diabetes, angina pectoris, hypertension, active hepatitis, etc.); 5) Prior or present participation in other psychological therapies. Exclusion criteria for healthy controls : 1) Those suffering from schizophrenia spectrum disorders and/or autism spectrum disorders; 2) Those with severe brain injury or nervous system/physical disease ; 3) Those with high suicide risk; 4) Those with intelligence below the normal range.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ADHD Rating Scale, ADHD-RS (Self- Reported and Clinician-administered); | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical Global Impression Scale, CGI;Self-Rating Depression Scale, SDS;Self-rating Anxiety Scale, SAS;Hamilton Depression Scale, HAMD;Hamilton Anxiety Scale, HAMA;Emotion Regulation Questionnaire, ERQ;Difficulties in Emotion Regulation Scale, DERS;Automatic thoughts questionnaire, ATQ;Dysfunctional attitudes scale, DAS;World Health Organization Quality of Life- Brief Version, WHOQOL-BREF;Five Facet Mindfulness Questionaire, FFMQ;Perceived Stress Scale, PSS;Simplified Coping Style Questionnaire, SCSQ;Quick Delay Questionnaire, QDQ;Behavior Rating Inventory of Executive Function—Adult Version, BRIEF-A;Stroop Color and Word Test, SCWT;Continuous Performance Test - Identical Pairs, CPT-IP;General Self-Efficacy Scale, GSES;Sheehan Disability Scale, SDS;Global Assessment Function, GAF;Functional Near-Infrared Spectroscopy, fNIRS; | — |
Countries
China
Contacts
Peking University Sixth Hospital