lumbar degenerative disease
Conditions
Interventions
BPSF group:bilateral pedicle screw fixation
UPSF group:unilateral pedicle screw fixation
UPSFS group:unilateral pedicle screws plus contra-lateral translaminar facet screws fixation
Sponsors
The Third Affiliated Hospital of Southern Medical University
Eligibility
Sex/Gender
All
Age
30 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. The age range is 30-70 years old. 2. Patients with chronic low back pain or unilateral radicular symptoms in a single lower limb, who had been underwent at least 3 months of fail conservative therapies. 3. The patient's preoperative VAS score for back pain or leg pain should be =4 points for at least one item. 4. The following imaging features are met: Single-level lesions of the low lumbar spine consistent with the symptoms and signs, typical unilateral lumbar disc herniation or lumbar instability, lumbar spinal stenosis, lumbar spondylolisthesis (Meyerding Grade I), facet joint Weishaupt = Grade II, paravertebral muscle Goutallier = Grade III. 5. The patient agreed and voluntarily signed informed consent forms and were able to comply with study protocols and visit plans.
Exclusion criteria
Exclusion criteria: 1.Multisegmental lesions of lumbar spine. 2.Subjects were eligible for any of the following: Severe lumbar spine trauma in the last 6 months, complicated with spinal infection, tuberculosis, tumors, spinal fracture or deformity. Lumbar spondylolisthesis with degree II or above, or lumbar spondylolysis. Hypoplasia of pedicle, lamina or facet, spondylolysis, severe lumbar spinal stenosis requiring removal of most facet decompression or extensive bilateral fenestration. 3.Patients with severe osteoporosis (T-score =-2.5) or obesity (BMI =25 kg/m2). 4.SDS=63 points or SAS=60 points. 5.Patients during pregnancy and lactation. 6. Patients with severe underlying diseases or mental disorders who can not tolerate surgery. 7. A person known to have a disease that the investigator considers an impediment to entry into the study. 8. Those who could not comply with the study assessment or complete the questionnaire for various reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fusion rate;Radiological measurements; | — |
Secondary
| Measure | Time frame |
|---|---|
| visual analogue scale(VAS);Oswestry Disability Index(ODI);EQ-5D;SF-36;operation time;intraoperative blood loss;postoperative drainage;postoperative hospital stay;complications; | — |
Countries
China
Contacts
Public ContactQingchu Li
The Third Affiliated Hospital of Southern Medical University
Outcome results
None listed