Skip to content

To explore the clinical characteristics of immune-related adverse events after tumor immunotherapy and the pathogenesis of different inflammatory phenotypes

To explore the clinical characteristics of immune-related adverse events after tumor immunotherapy and the pathogenesis of different inflammatory phenotypes

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300072029
Enrollment
Unknown
Registered
2023-05-31
Start date
2023-05-25
Completion date
Unknown
Last updated
2023-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

checkpoint inhibitor-related Pneumonitis

Interventions

Case series:NA

Sponsors

Nanfang Hospital of Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Voluntary signing of informed consent (2) Over 18 years old (including 18 years old), both male and female (3) ECOG score: 0 ~ 4 points (4) Pathological diagnosis confirmed tumor (5) Full abdominal CT plain scan, CT enhancement and peripheral blood biochemical tests supported the diagnosis of irAEs (6) Patients who require immunotherapy according to the judgment of the treating physician (7) Subject compliance is good

Exclusion criteria

Exclusion criteria: (1) Patients who are using investigational immunotherapy drugs (2) Patients with adverse reactions caused by chemotherapy, targeted therapy and radiation therapy before immunotherapy (3) The researchers judged that it was not suitable to participate in this study

Design outcomes

Primary

MeasureTime frame
Inflammatory specific cytokines and population characteristics of immune cells;

Secondary

MeasureTime frame
Imaging;

Countries

China

Contacts

Public ContactDong Hangming

Nanfang Hospital of Southern Medical University

huidhm@126.com+86 186 8842 6705

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026