Atopic Dermatitis (AD)
Conditions
Interventions
Total course group:None
Non total course group:None
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1) Meet the 2014 consensus standards of the American Academy of Dermatology for atopic dermatitis 2) No gender limitation 3) Age 18 or older 4) At baseline follow-up, IGA=3 (0-4 for IGA scale, with 3 being moderate and 4 being severe) or EASI=7 5) Insufficient response to local drug therapy 6) Informed consent to the purpose and content of the research
Exclusion criteria
Exclusion criteria: 1) Take immunosuppressive or immunomodulatory drugs (such as systemic corticosteroids, cyclosporine, mycophenolate mofetil, IFN-?, JAK inhibitors, azathioprine, methotrexate, etc.) for other medical conditions during the 4 weeks prior to baseline follow-up 2) Use dupilumab for other diseases during the 16 weeks prior to baseline follow-up
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The Scoring Atopic Dermatitis (SCORAD) score;Investigator's global assessment (IGA) score;Eczema area and severity index, EASI;Dermatology life quality index (DLQI) score;Patient-oriented eczema measure, POEM;Anxiety self-rating scale;Atopic dermatitis control test, ADCT;Patient global assessment,PtGA;pp-NRS;Serum immunoglobulin E;Cytokines and chemokines;Skin flora;Gut microbiota;Eosinophil count; | — |
Countries
China
Contacts
Public ContactLi Wei
Huashan Hospital, Fudan University
Outcome results
None listed