Schizophrenia
Conditions
Interventions
Group of schizophrenia :None
Sponsors
Shanghai Mental Health Center
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: For schizophrenia patients: ? Meet the diagnosis of schizophrenia (ICD-10); ? Age 18-70; ? Having Olanzapine or other Antipsychotic drugs (Aripiprazole.Ziprasidone.Amsulpiride.Blonanserin etc) for at least 12 months (allow for combination with mood stabilizers and benzodiazepines); ?The patient and his/her guardian signed the informed consent.
Exclusion criteria
Exclusion criteria: ? Received various treatments for anorexia or binge eating in last 4 weeks; ?Pregnant or lactating women; ?Organic mental disorders and mental disorders caused by psychoactive substances and non-addictive substances; ?Other diseases affecting the mental state (such as chronic obstructive pulmonary disease, myocardial infarction, angina pectoris, stroke, painful joint disease, tumor and other serious physical diseases); ?Severe heart and kidney insufficiency and other basic diseases; ?Family history of metabolic diseases such as hypertension, diabetes and hyperlipidemia; ? Patients with non-prescribed treatment, cognitive dysfunction, contraindications to ppTMS and other impact assessments and safety assessments.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Long-interval intracortical inhibition;Activation in the prefrontal cortex; | — |
Secondary
| Measure | Time frame |
|---|---|
| Yale Food Addiction Scale;Ghrelin;Leptin;Orexin;Glucagon-Like Peptide-1;Cholecystokinin;agouti-related protein;Pro-opiomelanocortin;Tyrosine—tyrosine polypeptide;Insulin;Interleukin 1ß;Interleukin 6;Interleukin 10;Interleukin 17;Interleukin 27;Interferon a; | — |
Countries
China
Contacts
Public ContactJianhua Chen
Shanghai Mental Health Center
Outcome results
None listed