tuberculosis immune reconstitution inflammatory syndrome
Conditions
Interventions
Zinc supplementation group (intervention group):standard treatment and Zinc supplementation
no zinc supplementation group (control group):standard treatment without zinc supplementation
Sponsors
Shenzhen Third People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: a. Meet the diagnostic criteria for HIV-1 infection in the "Chinese AIDS Diagnosis and Treatment Guidelines" (2021 edition); b. Meet the national tuberculosis diagnostic criteria; c. Agree to participate in this study and sign an informed consent form after being fully informed; d. Have not received anti-HIV treatment before enrollment; e. Be an adult over 18 years old.
Exclusion criteria
Exclusion criteria: a. Currently undergoing or have started antiretroviral therapy for HIV; b. Have taken zinc supplements in the past month; c. Allergic or contraindicated to zinc and related supplements; d. Excluding children and pregnant women;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence rates of two groups of IRIS;Serum zinc concentration; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical remission rate of tuberculosis symptoms;safety assessment; | — |
Countries
china
Contacts
Public Contactfang zhao
Shenzhen Third People's Hospital, Second Hospital Affiliated to Southern University of Science and Technology
Outcome results
None listed