chronic heart failure
Conditions
Interventions
Shen Ge San Group:On the basis of standard Western medicine treatment (valsartan 40/80mg qd po, spironolactone 20mg qd/bid po, metoprolol 12.5mg/25mg qd/bid po
) combined with EECP treatment, take Shen Ge San twice a day, 3g each time
control group:On the basis of standard Western medicine treatment (valsartan 40/80mg qd po, spironolactone 20mg qd/bid po, metoprolol 12.5mg/25mg qd/bid po
) combined with EECP, take a placebo twice a day, 3g each time
Sponsors
Shanghai Jing'an District Shibei Hospital
Eligibility
Sex/Gender
All
Age
45 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1) Age: 45-85 years old; 2) Diagnostic criteria for Western medicine: Previous history of coronary heart disease, NYHA cardiac function grading as II - III; 3) Diagnostic criteria for traditional Chinese medicine: Main symptoms: palpitations, shortness of breath, wheezing when moving, conscious fear of cold, and lukewarm hands and feet. Secondary symptoms: Little urine and swelling, bloating and loose stools, and a pale blue complexion. Tongue pulse: The tongue is light and plump or has tooth marks, and the pulse is thick and thin or late. 2 essential items for the main symptom and 2 items for the secondary symptom 4) Agree to participate in the trial, and be able to adhere to follow-up and seek medical treatment at the hospital on their own; 5) Sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1) Individuals with bronchial asthma, chronic bronchitis, pulmonary heart disease, and chronic obstructive pulmonary disease; 2) Individuals with unstable blood pressure control; 3) Acute cardiac insufficiency; 4) Severe liver and kidney dysfunction, as well as heart failure caused by important organ failure such as kidney and liver; (Note: Liver function (ALT, AST, TB) = 2 times the upper normal limit, or blood creatinine = 176umol/L, blood potassium = 5.5mmol/L.) 5) Those with severe primary diseases such as endocrine and hematopoietic systems; 6) Pregnant or lactating women; 7) Individuals with allergic constitution or a history of allergies; 8) Individuals with mental disorders and unwillingness to cooperate; Patients with poor compliance who interrupt treatment before the prescribed observation period and cannot determine the efficacy; 9) Those with poor adherence to the research process;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardiac ultrasound;6-minute walk test; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical Symptom Score;Quality of life scores improved significantly; | — |
Countries
China
Contacts
Public Contactliuzhaojie
Shanghai Jing'an District Shibei Hospital
Outcome results
None listed