lung cancer
Conditions
Interventions
rScO2-guided group:When rScO2 decreases by more than 10% from the base value, timely regulatory measures should be taken, including determining whether the electrode position is accurate
adjust the depth of anesthesia
adjust the respiratory parameter settings and moderately increase the level of end-expiratory C02, making PaC02 slightly higher than 40mmHg
maintain MAP to fluctuate around 20% at pre anesthesia levels (volume therapy, vasoactive drugs)
non-rScO2-guided group:No measures taken when rScO2 change
Sponsors
People's Hospital of Ganyu District, Lianyungang City, Jiangsu Province
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) 65 = Age = 80 years old, regardless of gender; 2) Perform elective thoracoscopic radical surgery for lung cancer (with bronchial intubation); 3) The ASA score is from Level I to Level III; 4)18 kg/m2<BMI<30kg/m2; 5) Clearly understand, voluntarily participate in the study, and have their informed consent form signed by themselves.
Exclusion criteria
Exclusion criteria: Patients with any of the following conditions cannot be included in this study: Preoperative pulmonary infection or undergoing radiotherapy, chemotherapy, or immunotherapy; Preoperative hypoalbuminemia; hypoxemia Previous history of chronic lung disease and asthma; History of mental illness or nervous system disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Delirium incidence rate;Serum S100 ß Protein concentration;Serum NSE concentration; | — |
Secondary
| Measure | Time frame |
|---|---|
| the mean of rScO2; | — |
Countries
China
Contacts
Public ContactTengPeilan
People's Hospital of Ganyu District, Lianyungang City, Jiangsu Province
Outcome results
None listed