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A study of oxycodone in the optimal effective dose of ED90 for perioperative multimodal analgesia in elderly thoracoscopic patients

A study of oxycodone in the optimal effective dose of ED90 for perioperative multimodal analgesia in elderly thoracoscopic patients - Oxycodone in a study of perioperative multimodal analgesia ED90 in elderly thoracoscopic patients

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300071956
Enrollment
Unknown
Registered
2023-05-30
Start date
2023-05-08
Completion date
Unknown
Last updated
2023-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mass lesions of the lungs

Interventions

Intervention group:Intravenous oxycodone injection was given intraoperatively

Sponsors

Shengjing Hospital, China Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 85 Years

Inclusion criteria

Inclusion criteria: Elderly patients who chose elective thoracoscopic lobectomy under general anesthesia in Shengjing Hospital affiliated to China Medical University; Age 65 years and older; American Society of Anesthesiologists (ASA) grade I ~ III, cardiac function class I.~II (NYHA grade); Body mass index (BMI): 18.5-29.9 kg•m^2

Exclusion criteria

Exclusion criteria: 1. Patients who cannot tolerate single-lung ventilation; 2. Have a history of asthma or other respiratory diseases; 3. Patients with severe cardiovascular and cerebrovascular diseases, liver and kidney failure; 4. Patients with abnormal mental status and inability to cooperate; or inability to understand and express pain scorers; 5. Long-term use of opioids or nonsteroidal anti-inflammatory drugs, chronic pain, history of alcohol or drug abuse and non-cooperation; 6. Those who have recently used analgesic and sedative drugs, and those who are allergic, resistant or addicted to the drugs and related ingredients used in the experiment; 7. Severe surgical complications resulting in prolonged hospital stay (such as secondary surgery, respiratory failure, etc.).

Design outcomes

Primary

MeasureTime frame
Numeric Rating Scale, NRS;

Secondary

MeasureTime frame
(visual analogue scale, VAS);Ramsay sedation score;Brief Pain Inventory short form;Numeric Rating Scale, NRS;Number of occurrences of postoperative adverse reactions;

Countries

China

Contacts

Public ContactJun Chai

Shengjing Hospital, China Medical University

18842462065@163.com+86 189 4025 9928

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026