Gastric cancer
Conditions
Interventions
TLDG-NOSE:Complete laparoscopic radical resection of distal gastric cancer (D2) with transrectal or vaginal removal of the surgical specimen (no auxiliary incision in the anterior abdominal wall) and
LADG:Laparoscopic radical resection of distal gastric cancer (D2) with transabdominal incision.
Sponsors
Third Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 20 years old = age = 70 years old, regardless of gender, informed consent; The tumor was located in the middle and lower part of the stomach and was expected to undergo distal gastrectomy and D2 lymph node dissection. The clinical stage of the tumor was C/ycT1-3 N0-2M0; Maximum tumor diameter = 3 cm (male), = 5 cm (female); BMI < 25 kg/m2 (male), < 30 kg/m2 (female); Nutritional risk screening (NRS 2002) = 1 point There was no history of pelvic surgery; Gastric adenocarcinoma was diagnosed by endoscopic biopsy histopathology; Karnofsky score = 70, Eastern Cooperative Oncology Group (ECOG) performance status score = 2
Exclusion criteria
Exclusion criteria: Women who are unmarried and do not have children or plan to have children again, or women with acute gynecological infection or vaginal deformity; men with perianal diseases or anal stenosis; obese patients (male BMI > 25 kg/m2, female BMI > 30 kg/m2); preoperative imaging suggests distant organ metastasis, such as liver metastasis, lung metastasis, etc.;Patients with tumors complicated with acute gastrointestinal obstruction, perforation or bleeding, or requiring emergency surgery; patients with other malignant diseases or other malignant diseases within 5 years, or patients with other diseases requiring simultaneous surgery; patients with a history of continuous systemic corticosteroid or immunosuppressive drug therapy within 1 month;Severe heart, brain, liver, lung, kidney, hematopoietic system and other important organ diseases or dysfunction, can not be operated on.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative complications;overall survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative conversion to laparotomy rate;Postoperative abdominal pain scores;Time of first flatus after operation;Time of first food intake after surgery;Time of first defecation after operation;Average postoperative hospital stay;Assessment of postoperative quality of life; | — |
Countries
China
Contacts
Public ContactBo Wei
Third Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed