Postoperative analgesia
Conditions
Interventions
Group NS:injection of NS
Group Ropivacaine:injection of ropivacaine
Sponsors
Department of Anesthesiology,Zhongshan Hospital of Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1 patients aged 18-80 years, 2 ASA grade I-III, 3 first time hepatectomy due to hepatocellular carcinoma or hepatic hemangioma 4 there were one or more of the following abnormalities in the preoperative coagulation function test: international standard ratio (INR)=1.4, platelet count 38s, the activated partial thromboplastin time (APTT) should be within the normal range (200 IU/kg/d) 5 Use of anticoagulants or antiplatelet drug which did not satisfy the safe time of epidural block 6 large-scale hepatectomy (3 hepatic segments) due to the large tumor, and the anesthesiologist was concerned about the postoperative coagulation function, it was considered that epidural puncture should not be performed, 7 patients had enough language communication ability to complete postoperative follow-up, 8 patients volunteered to be tested and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1 history of local anesthetic allergy, 2 chronic pain, long-term use of opioids, 3 block site infection, 4 combined surgery (except hepatectomy plus cholecystectomy) , 5 pregnant or lactating women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Consumption of hydromorphone 24 h after operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| dermatomal sensory coverage;Consumption of hydromorphone 12 h after operation;NRS score;Incidence of rebound pain;Rescue dose of hydromorphone in PACU;The time of the first PCIA injection of analgesic after operation;the incidence of analgesia-related adverse events in PACU and 24 h postoperatively;QoR-15 score;adverse events related to nerve block; | — |
Countries
China
Contacts
Public ContactXiaoguang Zhang
Zhongshan Hospital Affiliated to Fudan University
Outcome results
None listed