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A prospective cohort study on ultrasound-guided chemical ablation combined with percutaneous microwave ablation for symptomatic uterine leiomyoma

A prospective cohort study on ultrasound-guided chemical ablation (CA) combined with percutaneous microwave ablation (PMWA) for symptomatic uterine leiomyomas - US-guided CA&PMWA for uterine leiomyomas

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300071888
Enrollment
Unknown
Registered
2023-05-29
Start date
2023-06-01
Completion date
Unknown
Last updated
2023-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

uterine leiomyomas

Interventions

Combined treatment group:CA combined with PMWA
Control Group:Percutaneous microwave ablation

Sponsors

ShangHai Tenth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Female reproductive age (18-45 years old). There are clinical symptoms such as pelvic compression and abnormal uterine bleeding, and both ultrasound and magnetic resonance imaging are diagnosed as uterine fibroids. Non menstrual period, pregnancy, and perimenopausal period. Patients who refuse surgical procedures and wish to preserve uterine integrity. Individuals who are knowledgeable and willing to participate in this study.

Exclusion criteria

Exclusion criteria: Patients with concomitant adenomyosis and endometriotic cysts. Individuals with severe bleeding and coagulation disorders, cardiopulmonary dysfunction, mental disorders, etc. who cannot tolerate local anesthesia surgery. Patients with biopsy tissue pathology indicating malignant lesions. Those who have incomplete evaluation materials due to various reasons. Patients who were lost during the follow-up process.

Design outcomes

Primary

MeasureTime frame
local ablation rate;

Secondary

MeasureTime frame
symptom relief rate;Anemia correction rate;lesion volume regression rate;

Countries

China

Contacts

Public ContactSong-Yuan Yu

Shanghai Tenth People's Hospital

236770584@qq.com+86 153 3715 2922

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026