Sepsis
Conditions
Interventions
intervention group:Starting from the day of enrollment, 1.6mg thymosin (Lidaxian) was subcutaneously injected q12h for a course of 7 days
control group:None
Sponsors
Peking Union Medical College Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: When patients meet all the following conditions, they can choose to enter the study: (1) Age 18 years or older; (2) Conforming to the 2016 American Society of Critical Care Medicine/European Society of Critical Care Medicine (SCCM/ESICM) Sepsis 3.0 definition criteria for sepsis, that is, fatal organ dysfunction caused by infection (Sequential (Infection related) organ failure score SOFA = 2), or the need for vasopressor drugs to maintain mean arterial pressure = 65mmHg and blood lactate level>2mmol/L after sufficient fluid resuscitation; (3) Lymphocyte count<1.0 × 10^9/L; (4) The patient or family member is able to understand the research protocol and is willing to participate in this study, providing written informed consent.
Exclusion criteria
Exclusion criteria: Complies with any one of the following (1) Age<18 years old; (2) Pregnancy or lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 28-day mortality; | — |
Countries
China
Contacts
Public ContactNa Cui
Peking Union Medical College Hospital
Outcome results
None listed