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The study on the therapeutic mechanism of endobronchial valve for severe chronic obstructive pulmonary disease based on CT quantitative analysis and radiomics

The study on the therapeutic mechanism of endobronchial valve for severe chronic obstructive pulmonary disease based on CT quantitative analysis and radiomics

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300071873
Enrollment
Unknown
Registered
2023-05-26
Start date
2023-05-26
Completion date
Unknown
Last updated
2023-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Obstructive Pulmonary Disease

Interventions

Observation group:None

Sponsors

Chinese PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Patients with severe COPD who have received EBV treatment; 2.Patients with pulmonary CT images and lung function test results.

Exclusion criteria

Exclusion criteria: Patients with bullae occupying more than 30% of the thoracic cavity.

Design outcomes

Primary

MeasureTime frame
Change in pulmonary function test (FEV1, FVC, RV, TLC, FEV1/FVC) after EBV treatment;—

Secondary

MeasureTime frame
Change in 6 minute walking distance after EBV treatment;Change in quantitative CT values (emphysema, lung parenchyma, vessels, airways, respiratory muscles) after EBV treatment;Pulmonary radiomic features before and after EBV treatment ;Predictive radiomics model of EBV treatment efficacy;Predictive clinical-CT model of EBV treatment efficacy;Adverse Events and Serious Adverse Events;—

Countries

China

Contacts

Public ContactLiang'an Chen

Chinese PLA General Hospital

Chenla301@263.net+86 10 5549 9227

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026