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Efficacy of levonorgestrel releasing intrauterine system as a postoperative maintenance therapy of uterine adenomyoma: a retrospective cohort study

Efficacy of levonorgestrel releasing intrauterine system as a postoperative maintenance therapy of uterine adenomyoma: a retrospective cohort study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300071865
Enrollment
Unknown
Registered
2023-05-26
Start date
2022-11-20
Completion date
Unknown
Last updated
2023-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

adenomyoma

Interventions

LNG-IUS only Group:N/A
Laparoscopic adenomyomectomy combined with intraoperative replacement of LNG-IUS Group :N/A
Adenomyomectomy + 3 months of GnRH-a pretreatment before placement of LNG-IUS Group :N/A

Sponsors

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
26 Years to 55 Years

Inclusion criteria

Inclusion criteria: Patients with a history of progressive dysmenorrhea or menorrhagia and was diagnosed as adenomyoma by pathology; Patients who underwent laparoscopic adenomyomectomy; Uterine volume less than 12 weeks of pregnancy; Patients consent for 3 months of GnRH-a treatment and LNG-IUS insertion.

Exclusion criteria

Exclusion criteria: Patients with cervical or endometrial malignant lesions after hysteroscopy or diagnostic curettage; Patients with extensive pelvic endometriosis; Patients have fertility requirements within two years; Patients with contraindications for placing intrauterine devices; Patients with incomplete important data and unable to obtain follow-up information; Patients with severe dysfunction of liver and renal function.

Design outcomes

Primary

MeasureTime frame
Visual analogue scale (VAS) score;

Secondary

MeasureTime frame
Uterine volume;Mirena ring carrying status;serum CA125 levels;hemoglobin;Side effect;

Countries

China

Contacts

Public ContactChangyu Wang

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

d202282214@hust.edu.cn+86 138 3823 1967

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026