adult heart disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 to 65 years; 2. Patients undergoing elective cardiac surgery with cardiopulmonary bypass. 3. aortic cross-clamping time greater than 120 minutes
Exclusion criteria
Exclusion criteria: 1. Patients who do not consent to join the study; 2. Patinets who have severe perioperative infection; 3. Emergent surgery; 4. Patients who require high dose pharmacological inotropic support before surgery; 5. Patients who require preoperative mechanical circulatory support such as intra-aortic balloon pump or extracorporeal membrane oxygenation; 6. Patient who need surgical ablation; 7. Patients who undergo deep hypothermic circulatory arrest surgery; 8. Patients who have pacemaker implantation or PCI one month before cardiac surgery; 9. Patients who have a history of abnormal thyroid function; 10. Patients who have a history of coronary artery disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cTn; | — |
Secondary
| Measure | Time frame |
|---|---|
| Automatic heart resuscitation;heart resuscitation time after cross-clamp;failure to wean from cardiopulmonary bypass;malignant arrhythmia;Myoglobin;CK-MB;LDH;CRP;cardioplegia volume;caridopulmonary bypass time;cross-clamp time;transfusion during surgery;transfusion postoperation;Vasoactive Inotropic Score (VIS);mechanical ventilation time;Length of ICU stay;Length of hospital stay;In-hospital mortality;Intraoperative Glucose Levels;Intraoperative potassium level;Intraoperative sodium level;Intraoperative calcium level;diastolic and contractile function of heart;pathology test of left atrial appendage; | — |
Countries
China
Contacts
Shanghai Chest Hospital