MDS
Conditions
Interventions
Case series:NA
Sponsors
The First Affiliated Hospital with Nanjing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1.Documented diagnosis of MDS, MDS/MPN according to WHO 2022 classification,confirmed by bone marrow morphology, immunophenotyping, cytogenetic and molecular tests. 2.Subject is = 18 years. 3.Eastern Cooperative Oncology Group (ECOG) score of 0, 1, or 2. 4.Vital organs are functioning normally or compensated, and the following standards are met: ALT/AST/TBIL=2 x ULN; Bun/Scr=1.25 x ULN; EKG and UCG do not show organic heart disease or heart failure. 5. Subject must sign an informed consent form stating that he or she understands the purpose, procedures and contents of the registry and voluntarily participates in the trial.
Exclusion criteria
Exclusion criteria: 1.Known history of diagnosis of other hematological malignancies including lymphoma, multiple myeloma, etc. 2.Prior history of non-hemalogical malignancies. 3.Combined with severe impairment of vital organs, including respiratory failure, heart failure, decompensated hepatic insufficiency, renal insufficiency, etc. 4.HIV serologically positive. 5.Subject has mental illness or other illnesses that cannot fully comply with experimental treatment or follow-up requirements.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| response to therapy; | — |
Secondary
| Measure | Time frame |
|---|---|
| overall survival;event-free survival;adverse events;quality of life; | — |
Countries
China
Contacts
Public ContactGuangsheng He
The First Affiliated Hospital with Nanjing Medical University
Outcome results
None listed