Total knee arthroplasty
Conditions
Interventions
Experimental group 1:Femoral nerve block was performed with 0.1% ropivacaine 20ml after operation
Experimental group 2:Femoral nerve block was performed with 0.2% ropivacaine 20ml after operation
Experimental group 3:After operation, femoral nerve block was performed with 0.1% ropivacaine and dexmedetomidine 10µg, a total of 20ml
Experimental group 4:After operation, femoral nerve block was performed with 0.1% ropivacaine and dexmedetomidine 50µg, a total of 20ml?
Experimental group 5:After operation, femoral nerve block was performed with 0.1% ropivacaine and dexmedetomidine 100µg, a total of 20ml
Experimental group 6:Femoral nerve block was performed with 0.1% ropivacaine 20ml after operation
Sponsors
Gansu Provincial Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age: 40-75 years old; 2. Gender is not limited; 3.ASA classification I ~ II; 4. Implement total knee replacement; 5. Can communicate normally and have certain cognitive ability.
Exclusion criteria
Exclusion criteria: 1.Patients with coagulation dysfunction; 2. Patients infected with puncture site; 3. Patients with myopathy and severe liver and kidney diseases; 4. Patients with multiple trauma; 5. Patients with sensory or motor nerve damage of lower limbs caused by surgery or trauma in the past; 6. Those who are allergic to the drug used or any of its components or to similar drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score;Analgesia duration; | — |
Secondary
| Measure | Time frame |
|---|---|
| Temperature sense;Sense of touch;Activity score;First time to get out of bed;Patient satisfaction;Surgeon satisfaction;Length of stay; | — |
Countries
China
Contacts
Public ContactYan Wenjun
Gansu Provincial Hospital
Outcome results
None listed