Pulmonary nodules
Conditions
Interventions
75mg pregabalin group:On the night of operation, the morning and evening of the first and second day after operation, one pregabalin capsule (75mg) and one placebo with the same shape and smell were t
150mg pregabalin group:On the night of operation, the morning and evening of the first and second day after operation, two pregabalin capsules (150mg) were taken orally
control group:On the night of operation, the morning and evening of the first and second day after operation, two placebos with the same shape and smell were taken orally
Sponsors
Department of Anesthesiology, Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1?Age 18-65 years old; 2? ASA?-?, BMI18-30 kg/?; 3?Elective VATS;
Exclusion criteria
Exclusion criteria: ? Unilateral pneumonectomy; ? There was sleep disorder before operation (Pittsburgh Sleep Quality Index score > 5). ? Taking sedatives and antidepressants for more than 3 months; ? allergic to pregabalin; ? Patients with abnormal liver and kidney function before operation; ? Drug and alcohol dependence; ? Failure to communicate normally: hearing impairment, language comprehension impairment, mental illness, etc. ? Unable to understand the content of the scale and refused to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of sleep disorder on the night of operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| AIS score;SMH score ;PSQI ;NRS score of surgical shoulder and incision;Ramsay ;Patient satisfaction score; | — |
Countries
China
Contacts
Public ContactZhao Linlin
Department of Anesthesiology, Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed