conscious sedation in blind nasotracheal intubation
Conditions
Interventions
Dexmetomidine Group(DEX):Intravenous infusion of dexmetomidine 1.0 µg / kg (completed in 15min)
Midazolam Group(MID):Intravenous injection of midazolam 0.02mg / kg
Sponsors
The Third Affiliated Hospital of Anhui Medical University, First People’s Hospital of Hefei
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) ASA grade ? ~ ?. 2) 18-65 years old. 3) patients with limited mouth opening in elective oral and maxillofacial surgery.
Exclusion criteria
Exclusion criteria: 1) mental nervous system disease; 2) severe cardiopulmonary disease; 3) skull base fracture; 4) preoperative use of sedation and analgesia; 5) abnormal blood coagulation; 6) history of sinusitis, nasal or paranasal sinus deformities.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intubation time; | — |
Secondary
| Measure | Time frame |
|---|---|
| PETCO2 immediately after successful intubation;Heart rate;Mean arterial pressure;Bispectral index;Cortisol;Norepinephrine;Epinephrine;ß- Endorphin;Intraoperative dosage of sufentanil;VAS pain score at 24 hours post surgery; | — |
Countries
China
Contacts
Public ContactYang Heng
The Third Affiliated Hospital of Anhui Medical University, First People’s Hospital of Hefei
Outcome results
None listed