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Risk factor analysis and predictive model construction of adverse events after thoracic surgery: the impact of dexmedetomidine on adverse events after thoracic surgery

Risk factor analysis and predictive model construction of adverse events after thoracic surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300071831
Enrollment
Unknown
Registered
2023-05-26
Start date
2023-05-27
Completion date
Unknown
Last updated
2023-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

carcinoma of the lungs

Interventions

Dex1:After induction, dexamethasone 0.2 µ G/kg/h to 30min before the end of operation
Dex2:After induction, dexamethasone 0.4 µ G/kg/h to 30min before the end of operation
Dex3:After induction, dexamethasone 0.8 µ G/kg/h to 30min before the end of operation

Sponsors

Henan Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1) Thoracoscopic radical resection of lung cancer was performed on a selective basis; 2) The anesthesia method is intravenous general anesthesia; 3) Female, aged 18-65; 4) ASA Class I-II.

Exclusion criteria

Exclusion criteria: 1) Previous PONV or motion sickness history; 2) Previous history of thoracic surgery; 3) Preoperative and postoperative radiotherapy and chemotherapy; 4) Serious cardiovascular and cerebrovascular diseases; 5) Severe liver and kidney dysfunction; 6) With mental illness.

Design outcomes

Primary

MeasureTime frame
Incidence of postoperative nausea and vomiting;

Secondary

MeasureTime frame
Incidence of postoperative nausea;Incidence of postoperative vomiting;VAS pain score;Sleep;Anxiety and depression scale;QOR Recovery Quality Rating Scale;PCIA press;Dose and time of remedy analgesic and antiemetic drugs;Postoperative adverse reactions such as hypertension, hypotension, bradycardia, respiratory depression and dizziness within 48 hours after operation;

Countries

China

Contacts

Public Contactzhangwei

Henan Provincial People's Hospital

489336146@qq.com+86 199 5530 9379

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026